Melanocortin

Melanotan II — Reconstitution & Dosage Calculator

Chemical Identification
Mol. Weight 1024.18 g/mol

What is Melanotan II?

Melanotan II (MT-2) is a synthetic analogue of the naturally occurring peptide hormone alpha-melanocyte-stimulating hormone (α-MSH). It acts on melanocortin receptors and has been studied for its effects on skin pigmentation (tanning), sexual function, and appetite suppression.

Research Dosing Parameters

  • Typical dose range: 500 mcg–1 mg per injection
  • Common vial size: 10 mg
  • Reconstitution: 2–5 mL bacteriostatic water
  • Loading phase: Daily injections in initial research protocols; then maintenance

How to Reconstitute Melanotan II

  1. Inject bacteriostatic water slowly into the lyophilized vial
  2. Swirl gently until fully dissolved — do not shake
  3. The solution should be clear and colorless
  4. Store at 2–8°C after reconstitution
  5. Use within 30 days; protect from light

FAQ

What is the difference between Melanotan I and Melanotan II? Melanotan I (afamelanotide) is more selective for the MC1 receptor and focused on pigmentation. Melanotan II acts on multiple melanocortin receptors (MC1, MC3, MC4) and has broader studied effects including libido.

How do I calculate Melanotan II units for a 500mcg dose? Enter your vial size (10mg), BAC water volume (e.g. 2mL), and dose (500mcg) in the calculator above to get exact syringe units.

How should I start with Melanotan II in research protocols? Research protocols typically begin at low doses (250mcg or less) and titrate upward to assess response before reaching a standard maintenance dose.

Melanotan II Reconstitution Calculator

Select the Total Syringe Volume
Enter the Quantity of Peptide
Peptide 1
mg
Enter the Quantity of Bacteriostatic Water
Enter the Quantity of Peptide in each dose
Formulate
25.0units
  • Draw 25 units for 250mcg doses
  • With a concentration of 1.00mg/mL, vial contains ~20 doses in 5mL.