What is PT-141?
PT-141, also known as Bremelanotide, is a synthetic peptide derived from Melanotan II. Unlike Melanotan II, PT-141 has been specifically researched for its effects on sexual function in both male and female research models. It acts primarily on the melanocortin-4 receptor (MC4R) in the central nervous system.
Research Dosing Parameters
- Typical dose range: 1–2 mg per injection
- Common vial size: 10 mg
- Reconstitution: 2–5 mL bacteriostatic water
- Note: Doses are often expressed in mg — use the mg toggle in the calculator
How to Reconstitute PT-141
- Use bacteriostatic water for reconstitution
- Inject slowly along the inner vial wall
- Gently swirl until fully dissolved
- Store at 2–8°C after reconstitution
- Use within 30 days
FAQ
What is the difference between PT-141 and Melanotan II? PT-141 is derived from MT-2 but has a cyclic structure that gives it different receptor selectivity. PT-141 focuses on MC4R (central sexual function), while MT-2 has broader melanocortin activity including pigmentation.
How do I calculate 1mg of PT-141 in syringe units? Switch the dose unit to “mg” in the calculator above, enter 1mg as your dose along with your vial size and BAC water volume to get exact units.
When is PT-141 typically administered in research protocols? Research protocols typically administer PT-141 approximately 45–60 minutes before the time of interest.