What is Tesamorelin?
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) consisting of the entire 44-amino acid sequence of endogenous GHRH with a trans-3-hexenoic acid group added. This modification improves its stability and half-life. Researchers study Tesamorelin for its effects on GH secretion and reduction of visceral adipose tissue (VAT).
Research Dosing Parameters
- Typical dose range: 1–2 mg per injection
- Common vial size: 2 mg
- Reconstitution: 2 mL bacteriostatic water (or supplied diluent)
- Injection frequency: Once daily in most research protocols
- Note: Use the mg unit toggle in the calculator for milligram doses
How to Reconstitute Tesamorelin
- Use the provided diluent or bacteriostatic water
- Inject slowly along the inner vial wall — do not inject directly onto the powder
- Swirl gently until completely dissolved; the solution should be clear
- Store reconstituted Tesamorelin at 2–8°C
- Use within 3 days once reconstituted (more stability-sensitive than some peptides)
FAQ
How is Tesamorelin different from Sermorelin? Both are GHRH analogues. Tesamorelin contains the full 44-amino acid GHRH sequence with a trans-3-hexenoic acid modification for stability, while Sermorelin is the first 29 amino acids. Tesamorelin has been specifically studied for visceral fat reduction.
How do I use mg units in the calculator for Tesamorelin? Toggle the dose unit from “mcg” to “mg” in the calculator above and enter 1 or 2 mg as your dose for accurate syringe unit calculations.
How quickly does Tesamorelin reconstitute? Tesamorelin dissolves relatively quickly. Gentle swirling for 30–60 seconds typically achieves a clear solution. Avoid shaking vigorously.