Nootropic

Semax — Reconstitution & Dosage Calculator

Chemical Identification
Mol. Weight 813.94 g/mol

What is Semax?

Semax is a synthetic peptide developed in Russia as a nootropic and neuroprotective agent. It is derived from a fragment of ACTH (4-10) with an additional Pro-Gly-Pro sequence added. Researchers study Semax for its ability to upregulate brain-derived neurotrophic factor (BDNF), enhance cognitive function, and provide neuroprotection.

Research Dosing Parameters

  • Typical dose range: 200–600 mcg per administration
  • Common vial size: 5 mg
  • Reconstitution: 2 mL bacteriostatic water
  • Administration routes: Intranasal or subcutaneous injection in research
  • Frequency: 1–2x daily in research protocols

How to Reconstitute Semax

  1. Inject bacteriostatic water slowly along the inner vial wall
  2. Gently swirl until fully dissolved
  3. Do not shake
  4. Store at 2–8°C; use within 30 days
  5. For intranasal use, dilution ratios may differ — consult research protocols

FAQ

What is the difference between Semax and N-Acetyl Semax? N-Acetyl Semax has an acetyl group added to the N-terminus which may improve stability and bioavailability, particularly for intranasal administration. Both are studied for similar cognitive enhancement effects.

Can Semax and Selank be used together? In research, Semax and Selank are sometimes studied in combination — Semax for cognitive enhancement and Selank for anxiolysis. Use the multi-peptide calculator feature to combine doses.

How do I calculate intranasal Semax dose in units? The calculator is configured for subcutaneous injection volumes. For intranasal use, specific formulation concentrations apply — enter your reconstitution details for accurate unit calculations.

Semax Reconstitution Calculator

Select the Total Syringe Volume
Enter the Quantity of Peptide
Peptide 1
mg
Enter the Quantity of Bacteriostatic Water
Enter the Quantity of Peptide in each dose
Formulate
25.0units
  • Draw 25 units for 250mcg doses
  • With a concentration of 1.00mg/mL, vial contains ~20 doses in 5mL.