What is Semaglutide?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. It is a 31-amino acid peptide analogue of human GLP-1 with approximately 94% sequence homology. Researchers study semaglutide for its effects on blood glucose regulation, appetite suppression, and metabolic function.
Research Dosing Parameters
- Typical starting dose: 250 mcg per week
- Common vial size: 5 mg
- Reconstitution: 2–5 mL bacteriostatic water
- Titration: Doses are typically titrated upward over several weeks in research protocols
How to Reconstitute Semaglutide
- Allow the vial to reach room temperature before reconstituting
- Inject bacteriostatic water slowly down the side of the vial
- Do not shake — gently roll or swirl until dissolved
- The solution should be clear and colorless
- Store reconstituted peptide at 2–8°C, use within 28 days
FAQ
What syringe size is best for semaglutide injections? A 100-unit (1mL) insulin syringe is most commonly used in research. Use the calculator above to determine exact units based on your concentration.
How do I calculate semaglutide units? Enter your vial size (e.g. 5mg), the BAC water volume you added, and your target dose in the calculator above. It will instantly show the syringe units to draw.
What is the difference between semaglutide and tirzepatide? Semaglutide is a GLP-1 agonist, while tirzepatide is a dual GLP-1/GIP agonist. Both are studied for metabolic research but have different mechanisms and dosing parameters.